ТОВ «НДП Ветеринарні біотехнології»
м. Харків, пр. Леніна, 40
+38 (057) 719-11-27
vet-bio@ukr.net
ENG
MilVAC

MilVAC

Inactivated vaccine for the prevention and treatment bovine mastitis «MilVAC».

Vaccine is a liquid with friable white precipitate, which is easily broken in a uniform suspension at shaking. The vaccine contains a complex of somatic protective antigens of production strains Staphylococcus aureus "StaS-15" and Staphylococcus saprophyticus "StSS-15" – 60 %;
– Glycerin (preservative) – 19.8%;
– Aluminum hydroxide – 10 %;
– Phosphate buffer (adjuvant) – 10 %;
– Formaldehyde – 0,05 %;
– Thiomersal – 0,01 %;
– Saponin – 0,04 %
 
One dose of the vaccine contains 5×109 CFU of Staphylococcus aureus "StaS-15" and 4×108 CFU of Staphylococcus saprophyticus "StSS-15".
 

Pharmaceutical form:

Suspension.
 

Immunobiological properties

After administration to the organism antigens contained in the vaccine activate multiple mechanisms of the immune system (macrophages, opsonins, interleukins, B-cells, etc.) that are involved in the production of specific antibodies. The vaccine provides an intensive immunity formation against staphylococci – pathologic agents of bovine mastitis at vaccinated animals throughout 14 days after re-vaccination, which persists to 3 months.
 

Animal species:

Cattle.
 

Indications for use:

The “MilVAC” vaccine is designed for prevention of clinical and subclinical mastitis, which are caused by Staphylococcus aureus и Staphylococcus saprophyticus pathogenic strains. The “MilVAC can be used for immunization of cows and heifers and lactating cows in disadvantaged and prosperous farms threatened by these diseases. The vaccine has therapeutic and immunostimulative properties.
 

Contraindications

The “MilVAC” vaccine is not used to the sick and weak animals.
 
Precautions for use: Work with the preparation does not require special safety measures. To stir before applying.
 
Interaction with other preparations: The “MilVAC” vaccine is not used in conjunction with drugs that have immunosuppressive properties.
 
Special instructions during pregnancy, lactation, egg production:
It is used without restrictions.
 

How to use and dosing

“MilVAC” vaccine is injected intramuscularly with the external surface of the thigh or to the lower third of the neck twice with an interval of 2-4 weeks, cows, heifers, and calves since 20 days of age (5.0 cm3). The second administration of vaccine to cows with calf and heifers shall be made not later than 3-4 weeks before the expected calving.
Collateral action is not observed.
 
Special warnings for individuals and staff that use the VIP. Work with the preparation does not require special safety measures. In case of accidental injection of the vaccine a person should consult a doctor.
 

Special safety measures for handling unused VIP, ways of its disposal and recycling:

Not required.
 

Expiration date

18 months from date of manufacture. The vaccine is used within 24 hours after opening the vial.
 

Storage and transport

In a dry, dark place at a temperature from 2°C to 8°C. Cannot be freezing.
 

Packing

Bottles of 10, 20, 25, 30, 50, 100, 200, 250, 400, and 450 cm3.
 
The name and location of owner of the registration certificate
Limited Liability Company «Scientific-and-Research Enterprise Veterinary Biotechnology», Kharkiv, Lenina Prospect, 40,
phone (057) 719-11-27, e-mail: vet-bio@ukr.net
 

Terms of issue:

Without prescription.
 

Additional information:

If the product does not comply with specification or any complications, the use of this product series is stopped and reported to the State Scientific-and-Control Institute of Biotechnology and Strains of Microorganisms (SSCIBSM) and the supplier (manufacturer). Two unopened vials of this series are simultaneously directed to SSCIBSM by the courier, in accordance with the "Guidance on the procedure for filing claims on biological products intended for use in veterinary medicine" from 03.06.1998. № at the following address: 03151, Kyiv, Donetskaya Str., 30, SSCIBSM.